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Prostaglandins and glucocorticoids are potent mediators of inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) exert their effects by inhibition of prostaglandin production. The pharmacological target of NSAIDs is cyclooxygenase (COX, also known as PGH synthase), which catalyses the first committed step in arachidonic-acid metabolism. Two isoforms(More)
For junior/senior/graduate-level courses in Computer Organization and Architecture in the Computer Science and Engineering departments. This text provides a clear, comprehensive presentation of the organization and architecture of modern-day computers, emphasizing both fundamental principles and the critical role of performance in driving computer design.(More)