William Sheehan

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The cardiopulmonary effects of the narcotic agonists morphine, meperidine, oxymorphone, and methadone and of the partial agonist pentazocine were examined in the pain-free adult horse. The drugs produced dysphoric followed by euphoric effects. Increases in heart rate, arterial blood pressure, and cardiac output were observed in all horses with all drugs.(More)
The cardiopulmonary effects of two xylazine-morphine sulfate drug combinations (mixtures) given IV were evaluated in horses. In horses given xylazine (0.66 mg/kg of body weight) and morphine sulfate (0.12 mg/kv) IV (experiment 1), there were significant (P less than 0.05) decreases in heart rate, cardiac output, and respiratory rate. Central venous pressure(More)
A combination of intramuscular xylazine plus intravenous guaifenesin and ketamine hydrochloride was evaluated as a method for chemical restraint and casting of the adult horse. This drug combination provided safe and rapid induction of the horse and uneventful recovery from lateral recumbency. Cardiopulmonary function remained within base-line values for(More)
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