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- Benjamin Feldman, Michael A. Gates, +5 authors William S. Talbot
- Nature
- 1998
The vertebrate body plan is established during gastrulation, when cells move inwards to form the mesodermal and endodermal germ layers. Signals from a region of dorsal mesoderm, which is termed the… (More)
The zebrafish EGF-CFC gene one-eyed pinhead (oep) is required zygotically for the formation of the ventral neuroectoderm, endoderm, and prechordal plate. Here we report that embryos lacking both… (More)
- David A Lyons, Hans-Martin Pogoda, +6 authors William S. Talbot
- Current Biology
- 2005
BACKGROUND
Myelin is critical for efficient axonal conduction in the vertebrate nervous system. Neuregulin (Nrg) ligands and their ErbB receptors are required for the development of Schwann cells,… (More)
- Mary Ann Thompson, David G. Ransom, +17 authors Leonard I. Zon
- Developmental biology
- 1998
In vertebrates, hematopoietic and vascular progenitors develop from ventral mesoderm. The first primitive wave of hematopoiesis yields embryonic red blood cells, whereas progenitor cells of… (More)
- William S. Talbot, Bill Trevarrow, +6 authors David Kimelman
- Nature
- 1995
The notochord is a midline mesodermal structure with an essential patterning function in all vertebrate embryos. Zebrafish floating head (flh) mutants lack a notochord, but develop with prechordal… (More)
In D. melanogaster a pulse of the steroid hormone ecdysone triggers the larval-to-adult metamorphosis, a complex process in which this hormone induces imaginal tissues to generate adult structures… (More)
The steroid hormone ecdysone triggers coordinate changes in Drosophila tissue development that result in metamorphosis. To advance our understanding of the genetic regulatory hierarchies controlling… (More)
The steroid hormone ecdysone directs Drosophila metamorphosis via three heterodimeric receptors that differ according to which of three ecdysone receptor isoforms encoded by the EcR gene (EcR-A,… (More)
- John H Postlethwait, Ian G. Woods, +6 authors William S. Talbot
- Genome research
- 2000
To help understand mechanisms of vertebrate genome evolution, we have compared zebrafish and tetrapod gene maps. It has been suggested that translocations are fixed more frequently than inversions in… (More)
- Chikara Meno, Kira Gritsman, +9 authors Hiroshi Hamada
- Molecular cell
- 1999
Mammalian lefty and zebrafish antivin form a subgroup of the TGF beta superfamily. We report that mouse mutants for lefty2 have an expanded primitive streak and form excess mesoderm, a phenotype… (More)