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The role of indoor plantings as allergen sources was assessed by direct sampling of interior air. Homes with 10 or more plants in one room and three University of Michigan greenhouses were studied by means of a dc-powered rotorod and separate Andersen viable sampler collections incubated at 23 degrees and 50 degrees C. Sequential 30 and 60 sec Andersen(More)
Nasal airway resistance (NAR) was assessed from the slope of pressure-glow curves obtained during normal nasal breathing. Volunteers were classified as atopic or nonatopic according to strict critera. 100 ppm NH3 was introduced into each nostril for periods ranging from 5 to 30 seconds with frequent NAR monitoring. A progressive increase in NAR responses(More)
The effective size of bioaerosols is the principal determinant of their behavior during takeoff, transport, and deposition. Collection methods involving impaction, impingement, and filtration allow recovery of increasingly small aerosol units and do so "per unit volume of processed air" with more or less well-defined efficiency. These principles offer(More)
Effects of window air-conditioner operation on intramural particle levels were assessed in the bedrooms of 20 homes and in 10 outpatient clinic examining rooms during late summer periods. At each site, pollen and spore collections in the mechanically cooled room and a normally ventilated counterpart were compared using volumetric impactors. Substantially(More)
Serial nasal, intracutaneous, or bronchial challenges were carried out with solutions containing 2- or 3-fold increments in histamine (H) or methacholine (Meth) concentration until nasal airway resistance (NAR) increased by more than 100%, a large intracutaneous reaction was elicited, or FEV1 decreased by 20% or more. Thirty nonatopic and 48 asymptomatic(More)
Outdoor air was drawn by a vacuum system through a 0.8 micron molecular membrane filter and a back-up, refrigerated condensor from 8 A.M. to 5 P.M. daily during the 1982 ragweed-pollen season. Sample sets from each day were collected and stored separately. Condensate was collected in a freezing jacket, thawed, refiltered through a 0.45 micron filter, and(More)
Most considerations of Aspergillus fumigatus prevalence have implied that patterns of occurrence observed within London hospitals are generally applicable. Since prevalence data are almost nonexistent elsewhere, this assumption remains untested. To provide a comparison relevant to North America, we have monitored thermotolerant fungi outside as well as at(More)
Theophylline interacts pharmacokinetically with a variety of other drugs. Recently enoxacin was found to change theophylline's disposition. In a four-subject, four-way crossover study enoxacin was administered every 12 hours at four levels (0, 25, 100, and 400 mg) for 14 doses. With the ninth dose of enoxacin, 200 mg theophylline was coadministered. Blood(More)