William R. B. Lionheart

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Electrical impedance tomography (EIT) is a noninvasive imaging technique which aims to image the impedance within a body from electrical measurements made on the surface. The reconstruction of impedance images is a ill-posed problem which is both extremely sensitive to noise and highly computationally intensive. The authors define an experimental(More)
In the inverse conductivity problem, as in any ill-posed inverse problem, regularization techniques are necessary in order to stabilize inversion. A common way to implement regularization in electrical impedance tomography is to use Tikhonov regularization. The inverse problem is formulated as a minimization of two terms: the mismatch of the measurements(More)
We show that electrical impedance tomography (EIT) image reconstruction algorithms with regularization based on the total variation (TV) functional are suitable for in vivo imaging of physiological data. This reconstruction approach helps to preserve discontinuities in reconstructed profiles, such as step changes in electrical properties at interorgan(More)
In this paper, we review some numerical techniques based on the linear Krylov subspace iteration that can be used for the efficient calculation of the forward and the inverse electrical impedance tomography problems. Exploring their computational advantages in solving large-scale systems of equations, we specifically address their implementation in(More)
PURPOSE OF REVIEW Electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring tool that allows real-time imaging of ventilation. The purpose of this article is to discuss the fundamentals of EIT and to review the use of EIT in critical care patients. RECENT FINDINGS In addition to its established role in describing the distribution(More)
Electrical impedance tomography (EIT) is a low-cost, noninvasive and radiation free medical imaging modality for monitoring ventilation distribution in the lung. Although such information could be invaluable in preventing ventilator-induced lung injury in mechanically ventilated patients, clinical application of EIT is hindered by difficulties in(More)
Magnetic induction tomography (MIT) attempts to image the electrical and magnetic characteristics of a target using impedance measurement data from pairs of excitation and detection coils. This inverse eddy current problem is nonlinear and also severely ill posed so regularization is required for a stable solution. A regularized Gauss-Newton algorithm has(More)
In this paper, we investigate the feasibility of applying a novel level set reconstruction technique to electrical imaging of the human brain. We focus particularly on the potential application of electrical impedance tomography (EIT) to cryosurgery monitoring. In this application, cancerous tissue is treated by a local freezing technique using a small(More)
X-ray imaging applications in medical and material sciences are frequently limited by the number of tomographic projections collected. The inversion of the limited projection data is an ill-posed problem and needs regularization. Traditional spatial regularization is not well adapted to the dynamic nature of time-lapse tomography since it discards the(More)