William P Lundergan

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BACKGROUND To determine whether matrix metalloproteinase-3 (MMP-3) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in gingival crevicular fluid (GCF) could serve as prognostic factors for the progression of periodontitis, we monitored GCF MMP-3 and TIMP-1 and periodontal status of selected sites in 40 medically healthy subjects over a 6-month period.(More)
The free gingival graft is a simple, predictable technique for increasing the zone of attached gingiva. Dentists interested in performing minor surgical procedures should include the free gingival graft in their armamentarium. Indications and contraindications have been established, but the decision regarding the adequacy of the attached gingiva remains one(More)
The rationale for using the Perceptual Ability Test (PAT) as a component in admissions decisions for dental schools is that candidates vary in an underlying aptitude that is predictive of degree of success in technique course performance and perhaps in clinical performance. There have been periodic attempts to identify tests that more directly measure(More)
The identification and the development of potential growth factors for the cells of the periodontal ligament is an important and novel stratagem for the regeneration of tissue destroyed by periodontal pathogens. The problem is that growth factors are difficult to synthesize, very immunogenic and expensive. The purpose of our study was to determine if(More)
The purpose of this study was to investigate the associations between gingival crevicular fluid (GCF) elastase levels, clinical measures of periodontal status, and metabolic control of diabetes in insulin dependent (type 1) diabetes (IDDM) and non-insulin dependent (type 2) diabetes (NIDDM) patients. Sixty patients were recruited from the Diabetes Center at(More)
BACKGROUND Research in medicine has shown that physicians have difficulty estimating the probability that a patient has a condition on the basis of available diagnostic evidence. They consistently undervalue baseline information about the patient relative to test information and are poor intuitive calculators of probability. The authors could not locate in(More)
Few studies have focused on the role of nutrition in periodontal disease. The purpose of this trial was to determine the effect of a nutritional supplement on gingival inflammation, bleeding, probing depth, clinical attachment level, carotenoid antioxidant level, and C-reactive protein. The test supplement, consisting of a standard multivitamin formula, as(More)
The purpose of this study was to determine the effectiveness of scaling and root planing using a closed and open approach (papilla reflection) with and without a locally delivered antibiotic (minocycline hydrochloride microspheres) in the treatment of moderate to advanced chronic periodontitis. Twenty-five periodontal recall patients with four or more(More)
A brief review of the literature finds that studies of digital dexterity fail to confirm that dental students or dentists possess aptitudes that are different from the general population or that those with higher aptitudes achieve superior levels of performance. It is suggested that the complex nature of modern dental practice requires such a broad range of(More)