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  • Akira Kitamura, William Marszalec, Jay Z. Yeh, Toshio Narahashi
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2003 (First Publication: 1 December 2000)
  • General anesthetics are thought to act on both excitatory and inhibitory neuronal pathways at both post- and presynaptic sites. However, the literature in these regards is somewhat controversial. TheExpand
  • Megumi Yamashita, William Marszalec, Jay Z. Yeh, Toshio Narahashi
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2006 (First Publication: 1 October 2006)
  • The effects of ethanol on the GABAA receptors, which are regarded as one of the most important target sites of ethanol, are very controversial, ranging from potentiation to no effect. The δExpand
  • Shigeki Moriguchi, Norifumi Shioda, +5 authors Toshio Narahashi
  • Medicine, Chemistry
  • Molecular Pharmacology
  • 2007 (First Publication: 1 February 2007)
  • Nicotinic acetylcholine receptors and N-methyl-d-aspartate (NMDA) receptors are known to be down-regulated in the brain of Alzheimer's disease patients. We have previously demonstrated that theExpand
  • William Marszalec, Gary L. Aistrup, Toshio Narahashi
  • Psychology, Medicine
  • Alcoholism, clinical and experimental research
  • 1999 (First Publication: 1 March 1999)
  • Numerous studies have indicated a correlation between ethanol intake and cigarette smoking in heavy drinkers. We have studied the underlying pharmacological basis of this relationship using culturedExpand