Consistent high-quality of papers published in " Toxicology and Applied Pharmacology " can only be maintained with the cooperation and dedication of a number of expert referees. The Editorswould like to thank all those who have donated the hours necessary to review, evaluate and comment on manuscripts; their conscientious efforts have enabled the journal to… (More)
The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4nmol) was most potent, reaching 100% tumor incidence with a shorter latency to… (More)
Selective production of rat mutant selenoprotein W with and without bound glutathione. Biochem. (2004) The uses of carcinogen-DNA adduct measurement in establishing mechanisms of mutagenesis and in chemoprevention. Effect of artificial mixtures of environmental polycyclic aromatic hydrocarbons present in coal tar, urban dust and diesel exhaust particulates… (More)
Humans are exposed to complex mixtures of polycyclic aromatic hydrocarbons in the atmosphere. We examined the long term effects of a standard reference material (SRM) 1649a over time on the metabolic activation and DNA adduct formation by two carcinogenic PAHs, benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) in the human mammary carcinoma derived cell line… (More)
There is considerable evidence that exposure to air pollution is harmful to health. In the U.S., ambient air quality is monitored by Federal and State agencies for regulatory purposes. There are limited options, however, for people to access this data in real-time which hinders an individual's ability to manage their own risks. This paper describes a new… (More)
Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic aromatic hydrocarbons. (2011) Light chain dependent self-association of dynein intermediate chain. J.
(2010) The crystal structure of dynein intermediate chain-light chain roadblock complex gives new insights into dynein assembly. Light chain dependent self-association of dynein intermediate chain. (2010) Uric acid as a central nervous system antioxidant.
dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds. NMR analysis of dynein light chain dimerization and interactions with diverse ligands. (2009) Electron-capture dissociation (ECD), collision-induced dissociation (CID) and ECD/CID in a linear radio-frequency-free magnetic cell.
(2005) Effect of a standardized complex mixture derived from coal tar on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture. (2005) Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture SRM 1649a. (2005) Diesel exhaust particles cause increased levels of DNA… (More)