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Inhibition of norepinephrine (NE) reuptake into noradrenergic nerves is a common therapeutic target in the central nervous system (CNS). In noradrenergic nerves, NE is oxidized by monoamine oxidase(More)
To assess the impact of hepatic or renal impairment on the pharmacokinetics (PK) of edivoxetine. Two separate multi-center, open-label studies with males and females were conducted. Subjects were(More)