William J. Sheehan

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IMPORTANCE Many preschool children develop recurrent, severe episodes of lower respiratory tract illness (LRTI). Although viral infections are often present, bacteria may also contribute to illness pathogenesis. Strategies that effectively attenuate such episodes are needed. OBJECTIVE To evaluate if early administration of azithromycin, started prior to(More)
PURPOSE OF REVIEW The aim of the present review was to discuss the epidemiology of inadequate asthma control with an examination of contributing environmental factors. RECENT FINDINGS Despite advances in asthma therapies, a proportion of patients with asthma continue to have difficulty in gaining adequate asthma control. Asthma severity and control in(More)
Previous studies suggest that children with egg allergy may be able to tolerate baked egg. Reliable predictors of a successful baked egg challenge are not well established. We examined egg white-specific IgE levels, skin-prick test (SPT) results, and age as predictors of baked egg oral food challenge (OFC) outcomes. We conducted a retrospective chart review(More)
Our work group report details the importance of pest allergen exposure in inner-city asthma. We will focus specifically on mouse and cockroach exposure. We will discuss how exposure to these pests is common in the inner city and what conditions exist in urban areas that might lead to increased exposure. We will discuss how exposure is associated with(More)
BACKGROUND The association between allergens in schools and childhood asthma has not been well studied, particularly in the United States. OBJECTIVE To investigate allergen exposure in schools compared with homes with a specific focus on children with asthma. METHODS Dust samples were collected from 46 rooms in 4 urban elementary schools (northeastern(More)
OBJECTIVES The forced expiratory volume in 1 second (FEV(1)) felt to be an objective measure of airway obstruction is often normal in asthmatic children. The forced expiratory flow between 25% and 75% of vital capacity (FEF(25-75)) reflects small airway patency and has been found to be reduced in children with asthma. The aim of this study was to determine(More)
T he treatment of eczema in the pediatric population can be a complex and dynamic process. A typical careplanmay includeover-the-counter andprescription topical agents, oral medications, as well as bathing and dietary recommendations. Inevitable disease fluctuations demand treatment modification, and thus parental and patient confusion can easily occur. Not(More)
Questions exist regarding the appropriate age for referral of an atopic child to an allergist for environmental skin prick testing. This study evaluates age-specific prevalence of sensitization to aeroallergens from infancy through adolescence. A total of 1394 patients were skin tested, with 57.2% being sensitized to at least 1 aeroallergen. In children(More)