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The seminal importance of DNA sequencing to the life sciences, biotechnology and medicine has driven the search for more scalable and lower-cost solutions. Here we describe a DNA sequencing technology in which scalable, low-cost semiconductor manufacturing techniques are used to make an integrated circuit able to directly perform non-optical DNA sequencing(More)
DNA containing unmethylated CpG motifs is intrinsically immunostimulatory, inducing the production of a variety of cytokines and chemokines by immune cells. The strong Th1 response triggered by CpG oligodeoxynucleotide (ODN) inhibits the development of Th2-mediated allergic asthma in mice. This work documents that CpG ODN-induced IL-12 production plays a(More)
pain is the most common cause of hospital admission in the United States. 1 It accounts for 5% to 10% of all emergency department visits. 2 In 35% to 40% of all hospital admissions for abdominal pain, the pain is nonspecific. 3 In some cases, surgical intervention may be required. Symptoms suggesting the need for surgical correction include a pain duration(More)
BACKGROUND Hemorrhagic shock is the leading cause of trauma-related death in the military setting. Definitive surgical treatment of a combat casualty can be delayed and life-saving fluid resuscitation might be necessary in the field. Therefore, improved resuscitation strategies are critically needed for prolonged field and en route care. We developed an(More)
INTRODUCTION Motorcycles have become an increasingly popular mode of transportation despite their association with a greater risk for injury compared with automobiles. Whereas the recent incidence of annual passenger vehicle fatalities in the United States of America (USA) has progressively declined, motorcycle fatalities have steadily increased in the past(More)
 No changes are allowed to your track schedule once it is finalized.  You must take at least one elective during the 3 rd year.  UTMB no longer issues or requires pagers. All students will provide cell numbers to each clerkship coordinator in order to receive text pages or calls for urgent or mandatory issues. On my honor, as a member of the UTMB(More)
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