This is a graduate course on discrete optimization. The course will survey a selection of fundamental topics in the area, with an emphasis on polyhedral combinatorics. The topics of the course include the Euclidean algorithm, lattices and integral basis methods, the ellipsoid algorithm and its consequences, polarity, integral polyhedra, matching, covering… (More)
The Mathematical Programming Society will publish the new journal Mathematical Programming Computation (MPC) beginning in 2009. The journal is devoted to computational issues in mathematical programming, including innovative software, comparative tests, modeling environments, libraries of data, and/or applications. A main feature of the journal is the… (More)
Numerical experiments for a parallel implementation of a branch-and-bound mixed 0͞1 integer programming code are presented. Among its features, the code includes cutting-plane generation at the root node, and employs a new branching-variable selection rule within the search tree. The code runs on a loosely-coupled cluster of workstations using TreadMarks as… (More)
BACKGROUND The structure, function and reaction mechanism of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) have been extensively studied. Based on these studies, three anion binding sites have been identified, one 'Ps' site (for binding the C-3 phosphate of the substrate) and two sites, 'Pi' and 'new Pi', for inorganic phosphate. According to the… (More)
MINIREVIEW Biosynthesis and function of phospholipids in Esch-erichia coli. COMMUNICATIONS Tubulin binds specifically to the signal-transducing proteins, G, and Gi.1. An engineered change in substrate specificity of ribulosebisphosphate carboxylase/oxygenase. Stimulation of glycine catabolism in isolated per-fused rat liver by calcium mobilizing hormones… (More)
Using everyday language, spatial concepts, visualizations, and his renowned " Feynman diagrams " instead of advanced mathematics, Feynman clearly and humorously communicates both the substance and spirit of QED to the layperson. A perennial bestseller by eminent mathematician G. Polya, How to Solve It will show anyone in any field how to think straight. In… (More)
We give sufficient conditions for a differential equation to have a given semisimple group as its Galois group.