William Hollingworth

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BACKGROUND Vertebroplasty is commonly used to treat painful, osteoporotic vertebral compression fractures. METHODS In this multicenter trial, we randomly assigned 131 patients who had one to three painful osteoporotic vertebral compression fractures to undergo either vertebroplasty or a simulated procedure without cement (control group). The primary(More)
CONTEXT Back and neck problems are among the symptoms most commonly encountered in clinical practice. However, few studies have examined national trends in expenditures for back and neck problems or related these trends to health status measures. OBJECTIVES To estimate inpatient, outpatient, emergency department, and pharmacy expenditures related to back(More)
Trust and confidence are critical to the success of health care models. There are two main methods for achieving this: transparency (people can see how the model is built) and validation (how well the model reproduces reality). This report describes recommendations for achieving transparency and validation developed by a taskforce appointed by the(More)
BACKGROUND AND PURPOSE Proton MR spectroscopy ((1)H-MR spectroscopy) is a potentially useful adjunct to anatomic MR imaging in the characterization of brain tumors. We performed an updated systematic review of the evidence. METHODS We employed a standardized search strategy to find studies published during 2002-2004. We reviewed studies measuring(More)
BACKGROUND A previous randomised controlled trial reported greater efficacy of surgery than of splinting for patients with carpal tunnel syndrome. Our aim was to compare surgical versus multi-modality, non-surgical treatment for patients with carpal tunnel syndrome without denervation. We hypothesised that surgery would result in improved functional and(More)
STUDY DESIGN Prospective cohort study of randomly selected Veterans Affairs out-patients without baseline low back pain (LBP). OBJECTIVE To determine predictors of new LBP as well as the 3-year incidence of magnetic resonance imaging (MRI) findings. SUMMARY OF BACKGROUND DATA Few prospective studies have examined clinical and anatomic risk factors for(More)
INTRODUCTION Helical computed tomography angiography (CTA) has become an established technique for evaluating atherosclerosis of the cerebrovascular arteries. However, the role of CTA in penetrating and blunt trauma to the carotid and vertebral arteries is not well defined. We conducted a systematic literature review to determine the diagnostic accuracy of(More)
Recent research has derived preference scores from the SF-36. We compare the practicality and construct validity of SF-36 derived preference scores with directly elicited time trade off (TTO) and visual analogue scale (VAS) scores. In this observational study, low back pain (LBP), patients were asked to complete disease specific, generic (SF-36), and health(More)
AIM To review abnormalities reported on plain radiographic examination of the lumbar spine in patients referred with low back pain by general practitioners. Additionally, we evaluated and stratified the prevalence of these abnormalities by age. Finally, the diagnostic impact of lumbar spine radiography for the diagnosis of degenerative change, fracture,(More)
STUDY DESIGN Prospective cohort study of randomly selected Veterans Affairs (VA) outpatients. OBJECTIVE To determine the prevalence of magnetic resonance imaging (MRI) findings in the lumbar spine among persons without current low back pain or sciatica and to examine which findings are related to age or previous back symptoms. SUMMARY OF BACKGROUND(More)