William G. Nichols

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OBJECTIVES Dolutegravir (DTG) has been studied in three trials in HIV treatment-naive participants, showing noninferiority compared with raltegravir (RAL), and superiority compared with efavirenz and ritonavir-boosted darunavir. We explored factors that predicted treatment success, the consistency of observed treatment differences across subgroups and the(More)
increasing quality and cost-effectiveness of computer application software has revolutionized the way organizations share and manage their information. Rather than develop custom information systems with their internal programming staffs, many businesses now purchase software available in standard " off-the-shelf " packages. A well-chosen standard package(More)
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