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Structural brain networks were constructed based on diffusion tensor imaging (DTI) data of 59 young healthy male adults. The networks had 68 nodes, derived from FreeSurfer parcellation of the cortical surface. By means of streamline tractography, the edge weight was defined as the number of streamlines between two nodes normalized by their mean volume.(More)
Sound is inherently a temporal and sequential signal. Experience with sound therefore may help bootstrap - i.e., provide a kind of "scaffolding" for - the development of general cognitive abilities related to representing temporal or sequential patterns. Accordingly, the absence of sound early in development may result in disturbances to these sequencing(More)
The bulk of clinical research on cochlear implants (CIs) has been intellectually isolated from the mainstream of current research and theory in neuroscience, cognitive psychology and developmental neuropsychology. As a consequence, the major clinical research issues have been narrowly focused on speech and language outcomes and efficacy of cochlear(More)
OBJECTIVE To understand better the relation between media violence exposure, brain functioning, and trait aggression, this study investigated the association between media violence exposure and brain activation as measured by functional magnetic resonance imaging (fMRI) in groups of normal adolescents and adolescents with disruptive behavior disorder (DBD)(More)
PURPOSE This study investigated the feasibility and efficacy of a working memory training program for improving memory and language skills in a sample of 9 children who are deaf (age 7-15 years) with cochlear implants (CIs). METHOD All children completed the Cogmed Working Memory Training program on a home computer over a 5-week period. Feasibility and(More)
Adolescents with disruptive behavior disorder (DBD) and controls were investigated using an optimized MR diffusion tensor imaging (DTI) protocol in order to assess any possible structural abnormalities associated with DBD. Thirty-six patients and 40 normal subjects were examined. The extracted diffusion fractional anisotropy (FA) results demonstrate that(More)
OBJECTIVE To investigate the independent and combined contributions of neurocognitive and family functioning to mother-reported behavior problems in children with sickle cell disease (SCD) and evaluate the factor structure of the Family Environment Scale (FES) with African American families. METHOD The study sample included 289 children enrolled in the(More)
OBJECTIVE To conduct a prospective case-controlled study of pediatric inpatients referred for consultation in a tertiary care children's medical center. METHOD Referrals (n = 104) were matched with nonreferrals (n = 104) for age (4 to 18 years), gender, and illness type/severity and completed parent- and self-report (dependent on age) behavioral rating(More)
A large body of clinical research over the last decade demonstrates that cochlear implants work and provide significant speech and language benefits to profoundly deaf adults and prelingually deaf children. The most challenging research problem today is that cochlear implants do not work equally well for everyone who has a profound hearing loss and cochlear(More)
Diffusion tensor imaging (DTI) has been used for mapping the structural network of the human brain. The network can be constructed by choosing various brain regions as nodes and fiber tracts connecting those regions as links. The structural network generated from DTI data can be affected by noise in the scans and the choice of tractography algorithm. This(More)