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Structural brain networks were constructed based on diffusion tensor imaging (DTI) data of 59 young healthy male adults. The networks had 68 nodes, derived from FreeSurfer parcellation of the cortical surface. By means of streamline tractography, the edge weight was defined as the number of streamlines between two nodes normalized by their mean volume.(More)
Sound is inherently a temporal and sequential signal. Experience with sound therefore may help bootstrap - i.e., provide a kind of "scaffolding" for - the development of general cognitive abilities related to representing temporal or sequential patterns. Accordingly, the absence of sound early in development may result in disturbances to these sequencing(More)
Adolescents with disruptive behavior disorder (DBD) and controls were investigated using an optimized MR diffusion tensor imaging (DTI) protocol in order to assess any possible structural abnormalities associated with DBD. Thirty-six patients and 40 normal subjects were examined. The extracted diffusion fractional anisotropy (FA) results demonstrate that(More)
OBJECTIVE To determine the demographic characteristics, medical features, psychological profile, and natural history of children with chronic fatigue. DESIGN Case control study. SETTING Pediatric Infectious Diseases Clinic of Kosair Children's Hospital, 1990 to 1992. PARTICIPANTS Forty-four patients referred for persistent fatigue were evaluated.(More)
OBJECTIVE To understand better the relation between media violence exposure, brain functioning, and trait aggression, this study investigated the association between media violence exposure and brain activation as measured by functional magnetic resonance imaging (fMRI) in groups of normal adolescents and adolescents with disruptive behavior disorder (DBD)(More)
The bulk of clinical research on cochlear implants (CIs) has been intellectually isolated from the mainstream of current research and theory in neuroscience, cognitive psychology and developmental neuropsychology. As a consequence, the major clinical research issues have been narrowly focused on speech and language outcomes and efficacy of cochlear(More)
PURPOSE To evaluate the family environments of children with cochlear implants and to examine relationships between family environment and postimplant language development and executive function. METHOD Forty-five families of children with cochlear implants completed a self-report family environment questionnaire (Family Environment Scale--Fourth Edition;(More)
OBJECTIVE To conduct a prospective case-controlled study of pediatric inpatients referred for consultation in a tertiary care children's medical center. METHOD Referrals (n = 104) were matched with nonreferrals (n = 104) for age (4 to 18 years), gender, and illness type/severity and completed parent- and self-report (dependent on age) behavioral rating(More)
Progress in biomedical technology (cochlear, vestibular, and retinal implants) has led to remarkable success in neurosensory restoration, particularly in the auditory system. However, outcomes vary considerably, even after accounting for comorbidity-for example, after cochlear implantation, some deaf children develop spoken language skills approaching those(More)
BACKGROUND To evaluate the effect of atomoxetine (ATX) on attention-deficit/hyperactivity disorder (ADHD) and comorbid social anxiety disorder in adults. METHODS Randomized, double-blind, placebo-controlled, conducted in adults with ADHD and social anxiety disorder. Patients received 40-100 mg ATX (n=224) or placebo (n=218) for 14 weeks following a 2-week(More)