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Structural brain networks were constructed based on diffusion tensor imaging (DTI) data of 59 young healthy male adults. The networks had 68 nodes, derived from FreeSurfer parcellation of the cortical surface. By means of streamline tractography, the edge weight was defined as the number of streamlines between two nodes normalized by their mean volume.(More)
Sound is inherently a temporal and sequential signal. Experience with sound therefore may help bootstrap - i.e., provide a kind of "scaffolding" for - the development of general cognitive abilities related to representing temporal or sequential patterns. Accordingly, the absence of sound early in development may result in disturbances to these sequencing(More)
OBJECTIVE To understand better the relation between media violence exposure, brain functioning, and trait aggression, this study investigated the association between media violence exposure and brain activation as measured by functional magnetic resonance imaging (fMRI) in groups of normal adolescents and adolescents with disruptive behavior disorder (DBD)(More)
The bulk of clinical research on cochlear implants (CIs) has been intellectually isolated from the mainstream of current research and theory in neuroscience, cognitive psychology and developmental neuropsychology. As a consequence, the major clinical research issues have been narrowly focused on speech and language outcomes and efficacy of cochlear(More)
Progress in biomedical technology (cochlear, vestibular, and retinal implants) has led to remarkable success in neurosensory restoration, particularly in the auditory system. However, outcomes vary considerably, even after accounting for comorbidity-for example, after cochlear implantation, some deaf children develop spoken language skills approaching those(More)
BACKGROUND To evaluate the effect of atomoxetine (ATX) on attention-deficit/hyperactivity disorder (ADHD) and comorbid social anxiety disorder in adults. METHODS Randomized, double-blind, placebo-controlled, conducted in adults with ADHD and social anxiety disorder. Patients received 40-100 mg ATX (n=224) or placebo (n=218) for 14 weeks following a 2-week(More)
OBJECTIVE To investigate the independent and combined contributions of neurocognitive and family functioning to mother-reported behavior problems in children with sickle cell disease (SCD) and evaluate the factor structure of the Family Environment Scale (FES) with African American families. METHOD The study sample included 289 children enrolled in the(More)
PURPOSE This study investigated the feasibility and efficacy of a working memory training program for improving memory and language skills in a sample of 9 children who are deaf (age 7-15 years) with cochlear implants (CIs). METHOD All children completed the Cogmed Working Memory Training program on a home computer over a 5-week period. Feasibility and(More)
Adolescents with disruptive behavior disorder (DBD) and controls were investigated using an optimized MR diffusion tensor imaging (DTI) protocol in order to assess any possible structural abnormalities associated with DBD. Thirty-six patients and 40 normal subjects were examined. The extracted diffusion fractional anisotropy (FA) results demonstrate that(More)
This study examined the frequency and type of behavioral problems in 50 children with myelodysplasia and investigated the hypothesized roles of central nervous system (CNS) functioning and family functioning in behavioral problem outcome. The findings revealed that 50% of the children with myelodysplasia had a behavioral problem pattern and another 2% had(More)