William Franklin

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The use of a postlabeling method to characterize and to detect infrequent base modifications in DNA is outlined. This method has the advantage that low levels of DNA modifications, approximately 1 modified base per 10(5) nucleotides, can be detected. Moreover, a broad spectrum of modification can be identified by using this methodology. The basis for the(More)
Fifteen guanacos were introduced to Staats Island in the Falklands/Malvinas archipelago from Patagonia in the 1930s. Twenty five years later, the population was culled from 300 to 10-20 individuals, but quickly rebounded to a population of almost 400 animals that today retain the genetic signature of the founding event and later bottleneck. The goals of(More)
By the mid-1900s the guanaco (Lama guanicoe) approached extinction in southern South America due to habitat destruction and hunting. In order to maintain the ecological prominence of this iconic species, as well as assist in the management of populations that are emerging economically while increasing in conservation value, accurate and potentially rapid(More)
We report a precision measurement of the deuteron tensor analyzing powers T(20) and T(21) at the MIT-Bates Linear Accelerator Center. Data were collected simultaneously over a momentum transfer range Q=2.15-4.50 fm(-1) with the Bates Large Acceptance Spectrometer Toroid using a highly polarized deuterium internal gas target. The data are in excellent(More)
The speech-sound production of severely language-impaired children was monitored in a longitudinal study. In order to generalize findings, acoustical, phonemic, and clinical observation data were collected from 30 children. Results showed that speech-sound acquisition goes through a hierarchical sequence of development and that speech-sound production will(More)
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