William F Brazerol

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Serum vitamin B-12 and urinary methylmalonic acid (MMA) concentrations were determined in 62 healthy infants aged 1-6 mo. Urinary MMA was inversely correlated with serum vitamin B-12 concentrations (r = -0.550, p less than 0.001); serum vitamin B-12 was higher (p less than 0.001) and urinary MMA concentrations were lower (p less than 0.001) in formula-fed(More)
Age- and sex-specific bone mineral measures have not been available for healthy preschool children. We determined bone mineral content (BMC) and bone width in 89 children 1 to 6 years of age using direct photon absorptiometry at the one-third distal radius site. The BMC increased significantly with age, and bone width increased slightly with age. After(More)
We tested the hypothesis that repeated whole body suberythemal ultraviolet B (UVB) exposure would result in less increase of serum 25-hydroxyvitamin D (25OHD) concentrations in black compared with white young adults with no significant change or racial differences in serum calciotropic hormones concentrations. Thirteen white and 7 black adults ranging from(More)
OBJECTIVE Our purpose was to determine whether obstetric patients with unexplained elevated maternal serum alpha-fetoprotein levels from an indigent clinic population are at increased risk for adverse perinatal outcome compared with similar patients with normal values. STUDY DESIGN Perinatal outcomes from inner-city obstetric patients with unexplained(More)
We reported that bone mineral content (BMC) in the first 6 mos of life was decreased in breast-fed infants without vitamin D, vs breast with D or formula-fed infants. No data have been reported on BMC and bone width (BW) in healthy children from 1 to 7 yrs. We hypothesized that BMC increases with age and is lower in females, with no difference by previous(More)
THE INTERRELATIONSHIP BETWEEN LINOLEIC AND LINOLENIC 708 ACIDS IN NEONATES MAINTAINED ON TPN INCLUDING SAFFLOWER OIL. N.P. Simon, D.H. Adamkin, (Sponsored by B.F. Andrews). Univ. of Louisville, Dept. of Pediatrics, Louisville, Ky. An investigational 20% safflower oil emulsion with increased linolenic acid (351.5%) was evaluated in ten neonates and compared(More)
D deficiency rickets has been reported mainly in black infants, and we have reported lower serum 25-hydroxyvitamin D (25-OHD) in black vs white infants. We hypothesized that race dependent differences in the response of D metabolites to chronic SE UVB may explain these observations. Prior to infant studies, we determined the responses of serum 260HD, 24,(More)
Factors affecting 25-hydroxyvitamin D (25OHD) response to chronic sub-erythemal ultraviolet (UV) exposure have not been studied in adults or infants. This study was a pilot one in adults before infant studies: we hypothesized that serum parathyroid hormone (PTH), vit. D binding protein (DBP), 25OHD & race affect the 25OHD response to chronic suberythemal(More)
Infants of diabetic mothers have a higher incidence of neonatal hypocalcemia and hypomagnesemia. Decreased BMC has been reported in diabetic patients, with bone mineralization of IDM has not been; systematically evaluated. The present study was done to test the hypothesis that decreased neonatal BMC in IDMs is correlated with poor control of diabetes during(More)
Ca and mineral requirements in term and premature infants are the subject of recent studies. We proposed to establish reference values for Ca and P regulating agents in healthy term formula fed infants. Ca, iCa, P, Mg, 1,25(OH)2 vitamin D (1,25D), 25 OH vitamin D (25D), parathyroid hormone (PTH), calcitonin (CT) and alkaline phosphatase (Alk Phos) were(More)
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