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Adenylosuccinase deficiency is an autosomal recessive inherited defect of purine synthesis. In enzyme deficient patients, two normally undetectable compounds, succinylaminoimidazole carboxamide riboside and succinyladenosine, accumulate in urine, cerebrospinal fluid and, to a minor extent, in plasma. Analysing 150 highly selected urine specimens from(More)
During 2012, global detection of a new norovirus (NoV) strain, GII.4 Sydney, raised concerns about its potential effect in the United States. We analyzed data from NoV outbreaks in 5 states and emergency department visits for gastrointestinal illness in 1 state during the 2012-13 season and compared the data with those of previous seasons. During August(More)
reproduction in any medium, provided the original work is properly cited. Objective To improve the method of automated retrieval of surveillance-related literature from a wide range of indexed repositories. Introduction The ISDS Research Committee (RC) is an interdisciplinary group of researchers interested in various topics related to disease surveillance.(More)
reproduction in any medium, provided the original work is properly cited. Objective Preliminary analysis was completed to define, identify, and track the trends of drug overdoses (OD), both intentional and unintentional, from emergency department (ED) and urgent care (UC) chief complaint data. Introduction The State of Ohio, as well as the country, has(More)
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