William E Kraus

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Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial.

Christopher M. O'Connor, David Joshua Whellan, +14 authors Ileana L. Piña
JAMA
2009

CONTEXT Guidelines recommend that exercise training be considered for medically stable outpatients with heart failure. Previous studies have not had adequate statistical power to measure the effects… (More)

Effects of the amount and intensity of exercise on plasma lipoproteins.

William E Kraus, Joseph A. Houmard, +9 authors Cris A. Slentz
The New England journal of medicine
2002

BACKGROUND Increased physical activity is related to reduced risk of cardiovascular disease, possibly because it leads to improvement in the lipoprotein profile. However, the amount of exercise… (More)

Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy.

Anshu B. Mathur, Amy M. Collinsworth, William Monty Reichert, William E Kraus, George A. Truskey
Journal of biomechanics
2001

This study evaluated the hypothesis that, due to functional and structural differences, the apparent elastic modulus and viscous behavior of cardiac and skeletal muscle and vascular endothelium would… (More)

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by…

Deborah M. Muoio, Paul S Maclean, +7 authors William E Kraus
The Journal of biological chemistry
2002

Ablation of peroxisome proliferator activated receptor (PPAR) alpha, a lipid-activated transcription factor that regulates expression of beta-oxidative genes, results in profound metabolic… (More)

Interventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart Association.

Nancy T Artinian, Gerald F. Fletcher, +22 authors Lora E. Burke
Circulation
2010

Copyright © 2010 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX… (More)

Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial.

Kathryn E. Flynn, Ileana L. Piña, +13 authors Kevin P. Weinfurt
JAMA
2009

CONTEXT Findings from previous studies of the effects of exercise training on patient-reported health status have been inconsistent. OBJECTIVE To test the effects of exercise training on health… (More)

Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease.

Aarti A. Kenjale, Katherine L. Ham, +7 authors Jason D. Allen
Journal of applied physiology
2011

Peripheral arterial disease (PAD) results in a failure to adequately supply blood and oxygen (O(2)) to working tissues and presents as claudication pain during walking. Nitric oxide (NO)… (More)

Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.

Svati H. Shah, James R. Bain, +9 authors William E Kraus
Circulation. Cardiovascular genetics
2010

BACKGROUND Molecular tools may provide insight into cardiovascular risk. We assessed whether metabolites discriminate coronary artery disease (CAD) and predict risk of cardiovascular events. … (More)

Effect of the volume and intensity of exercise training on insulin sensitivity.

Joseph A. Houmard, Charles J. Tanner, Cris A. Slentz, Brian D. Duscha, Jennifer S McCartney, William E Kraus
Journal of applied physiology
2004

Physical activity enhances insulin action in obese/overweight individuals. However, the exercise prescription required for the optimal enhancement is not known. The purpose of this study was to test… (More)

Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients.

Steven A Rosenberg, Michael R. Elashoff, +18 authors Eric J. Topol
Annals of internal medicine
2010

BACKGROUND Diagnosing obstructive coronary artery disease (CAD) in at-risk patients can be challenging and typically requires both noninvasive imaging methods and coronary angiography, the gold… (More)

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