William A. Hillenbrand

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Various concepts for measuring (by means of biosensors incorporated into pacemakers) biologic parameters to determine the appropriate pacing rate are reviewed. They are pH, stimulus-to-T-wave interval, blood temperature, intercardiac blood pressure change, venous oxygen saturation, intercardiac impedance (stroke volume, ejection rate, preejection interval),(More)
Background: To explore the hypothesis that tissue iron and reactive oxygen species, including superoxide (O2  ), mediate acute inflammatory and late hyperplastic responses to vascular injury, we studied experimental over-distension of normal carotid and femoral arteries in dogs. Experimental design: Arterial segments isolated in situ were distended with(More)
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