Willem Pondaag

Learn More
OBJECTIVE Obstetric brachial plexus lesions may cause lifelong limitations of upper limb function. Nerve repair is widely advocated in infants who do not show spontaneous recovery. Typically, the suprascapular nerve (SSN) is involved in the lesion. Neurotization of the SSN routinely is performed, aiming at reinnervation of the infraspinatus muscle to(More)
Neonatal brachial plexus palsies may cause lifelong limitations to function of the upper limb. Early nerve reconstructive surgery may be indicated in selected cases. An overview is given of our current understanding of this type of nerve lesion in the developing child. The neuropathology of the injury is presented to provide a background for the(More)
BACKGROUND Expected survival is a major factor influencing extent of treatment for symptomatic spinal bone metastases (SBM). Predictive models have been developed, but their use can lead to over- or undertreatment.. The study objective was to identify prognostic factors associated with survival in patients with symptomatic SBM and to create a validated risk(More)
Obstetric brachial plexus lesions (OBPLs) are typically caused by traction to the brachial plexus during labor. The incidence of OBPL is about 2 per 1000 births. Most commonly, the C5 and C6 spinal nerves are affected. The prognosis is generally considered to be good, but the percentage of children who have residual deficits may be as high as 20% to 30%.(More)
Strong scientific validation for nerve reconstructive surgery in infants with Obstetric Brachial Plexus Palsy is lacking, as no randomized trial comparing surgical reconstruction versus conservative treatment has been performed. A systematic review of the literature was performed to identify studies that compare nerve reconstruction to conservative(More)
We report a boy with severe syndromic intellectual disability who has a de novo mutation in the ZMYND11 gene. Arguments for pathogenicity of this mutation are found in cases from the literature, especially several with 10p15.3 deletions, harbouring ZMYND11. Additional reports of ZMYND11 mutations in cases with syndromic intellectual disability are needed(More)
In 46 head-injured patients coagulation studies were performed immediately after admission. In 76% of all cases signs of disseminated intravascular coagulation (DIC) were found. DIC was related to the severity of the injury and outcome. It is suggested that DIC may be used as an important parameter in assessing craniocerebral trauma. In a previous report it(More)
Evaluation of risk factors for survival in patients surgically treated for symptomatic spinal epidural metastases (SEM). One hundred and six patients who were surgically treated for symptomatic SEM in a 10-year period in two cooperatively working hospitals were retrospectively studied for nine risk factors: age, gender, site of the primary tumor, location(More)
OBJECTIVE Options for nerve repair are limited in brachial plexus lesions with multiple root avulsions because an insufficient number of proximal nerve stumps are available to serve as lead-out for nerve grafts. End-to-side nerve repair might be an alternative surgical technique for repair of such severe lesions. In this technique, an epineurial window is(More)
PURPOSE To evaluate the value of computed tomographic (CT) myelography in the detection of root damage and differentiation of root avulsions from neurotmesis in a large cohort of patients with an obstetric brachial plexus lesion (OBPL). MATERIALS AND METHODS Institutional review board approval was obtained. Informed consent was waived by the medical(More)