Learn More
Type 1 von Willebrand disease (VWD) is characterized by a personal and family history of bleeding coincident with reduced levels of normal plasma von Willebrand factor (VWF). The molecular basis of(More)
Mike A. Laffan, Will Lester, James S. O’Donnell, Andrew Will, Robert Campbell Tait, Anne Goodeve, Carolyn M. Millarand David M. Keeling Centre for Haematology, Imperial College London, London,(More)
The molecular pathogenesis of type 1 von Willebrand disease (VWD) is uncertain in most patients. We examined 30 type 1 VWD families in the UK Haemophilia Centre Doctors' Organization study.(More)
This study tested the hypothesis that combination ion channel blockers of the transient outward current (I(to)) and the rapid component of the delayed rectifying current (I(Kr)) would produce greater(More)