Wilfrid Mazier

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Cellular activity in the brain depends on the high energetic support provided by mitochondria, the cell organelles which use energy sources to generate ATP. Acute cannabinoid intoxication induces amnesia in humans and animals, and the activation of type-1 cannabinoid receptors present at brain mitochondria membranes (mtCB1) can directly alter mitochondrial(More)
The islets of Langerhans comprise endocrine cells embedded in a microvasculature network that provides blood-borne and paracrine signals essential for pancreatic development and maintenance of islet functions. Apart from enabling blood flow to the islets and the transport of pancreatic hormones toward target organs, islet capillaries also guarantee(More)
The endocannabinoid system (ECS) functions to adjust behavior and metabolism according to environmental changes in food availability. Its actions range from the regulation of sensory responses to the development of preference for the consumption of calorically-rich food and control of its metabolic handling. ECS activity is beneficial when access to food is(More)
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