Wiley R Hall

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This study was conducted to evaluate the safety of l-theanine (Suntheanine) when administered as a dietary admixture to male and female Crl:CD (SD)GS BR rats at concentrations providing doses of 0, 1500, 3000 or 4000 mg/kg bw/day for 13 weeks. The study design was consistent with OECD Guideline 408 and USFDA Redbook II (1993) and GLP. There were no(More)
PURPOSE This was an open-label, dose-escalation trial of intratumoral administration of IL-4 Pseudomonas Exotoxin (NBI-3001) in patients with recurrent malignant glioma. PATIENTS AND METHODS A total of 31 patients with histologically verified supratentorial grade 3 and 4 astrocytoma were studied. Of these, twenty-five patients were diagnosed with(More)
Altered frequencies of alpha 1 antitrypsin phenotypes have been reported in patients with chronic pancreatitis, suggesting a possible genetic basis for individual susceptibility to this disease. Alpha 1 antitrypsin phenotypes, with particular regard to alcoholic pancreatitis, were studied. Patients with alcoholic pancreatitis were compared with alcoholic(More)
The lower esophageal high pressure zone of eight Rhesus monkeys was characterized by manometry and reflux testing. It was found to respond characteristically to pentagastrin infusions. After excision of the lower esophageal segment and tis replacement by a stomach tube, an apparently normal, functional high pressure zone was demonstrable within the(More)
Transplantation between non-identical humans has been limited by the requirement for chronic immunosuppression (CI). This study demonstrates in a nonhuman primate model that long-term acceptance of incompatible kidney allografts can be achieved without the use of CI. Following incompatible kidney transplantation, rhesus monkey recipients were given a 5-day(More)
BACKGROUND/AIMS Hypertriglyceridemia is an established cause of pancreatitis and has been suggested as a predisposing factor in alcohol and gallstone-induced pancreatitis. The aims of this study were to determine fasting and postprandial triglyceride levels of alcoholics with pancreatitis, alcoholics without pancreatitis, patients with previous gallstone(More)
Four cases of anaplastic carcinoma of the thyroid were diagnosed in 1,519 thyroid aspirates. All patients had unilateral or diffuse nodular enlargement of the thyroid. One patient had a concurrent grade 1 mucinous carcinoma of the ovary. Cytologically, the neoplasms were characterized by pleomorphic giant or spindle cells with multilobulated, single or(More)
This study compared the costs and benefits of brain tumor resection performed in an interventional MR suite using a 1.5-T Philips Gyroscan ACS-NT MR imager vs conventional operating room (OR) neurosurgical resection. Patient length of stay (LOS), hospital charges, total hospital costs, patient readmission rate, rate and interval of further medical(More)
BACKGROUND Known predictors of adverse outcomes in patients with moderate-severe TBI (msTBI) explain only a relatively small proportion of patient-related outcomes. The frequency and impact of intensive care unit complications (ICU-COMPL) on msTBI-associated outcomes are poorly understood. METHODS In 213 consecutive msTBI patients admitted to a Level I(More)