Wilbert Sibanda

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This paper presents an application of Multi-layer Perceptrons (MLP) neural networks to model the demographic characteristics of antenatal clinic attendees in South Africa. The method of cross-validation is used to examine the betweensample variation of neural networks for HIV prediction. MLP neural networks for classifying both the HIV negative and positive(More)
A Plackett-Burman design was employed to develop and optimize a novel crosslinked calcium-aluminum-alginatepectinate oilisphere complex as a potential system for the in vitro site-specific release ofMentha piperita, an essential oil used for the treatment of irritable bowel syndrome. The physicochemical and textural properties (dependent variables) of this(More)
A Two-Level Fractional Factorial design was employed to develop and optimize the combination of demographic characteristics that has the greatest effect on the spread of HIV in the South African population. HIV prevalence (dependent variable) was found to be highly sensitive to changes in the mother’s age (15-55years) and level of education (Grades 0-13)(More)
A Box-Behnken Design was employed to study the influence of boric acid, sodium sulfate, ammonia and n-propanol in the formulation of crosslinked ethylenic homopolymeric (CEH) gelispheres from native polyvinyl alcohol (PVA). The dependent variables studied included the size of the spherical gelispheres, drug encapsulation efficiency, in vitro dissolution(More)
Neural networks have been applied successfully to a broad range of fields such as finance, data mining, medicine, engineering, geology, physics and biology. In finance, neural networks have been used for stock market prediction, credit rating, bankruptcy prediction and economic indicator forecasts. In medicine, neural networks have been used extensively in(More)
In this study, a Central Composite Face Centered (CCF) design was employed to study the individual and interaction effects of demographic characteristics on the spread of HIV in South Africa. The demographic characteristics studied for each pregnant mother attending an antenatal clinic in South Africa, were mother's age, partner's age, mother's level of(More)
In this study, Central composite face-centered and Box–Behnken designs were employed to study the main and interaction effects of demographic characteristics on the risk of HIV in South Africa. The demographic characteristics studied for each pregnant mother attending an antenatal clinic in South Africa were mother’s age, partner’s age (father’s age),(More)
This research paper covers the development of an HIV risk scorecard using SAS Enterprise Miner#8482;. The HIV risk scorecard was developed using the 2007 South African annual antenatal HIV and syphilis seroprevalence data. Antenatal data contains various demographic characteristics for each pregnant woman, such as pregnant woman's age, male sexual partner's(More)
BACKGROUND Few studies have investigated the management of human immunodeficiency virus (HIV)-associated end-stage renal failure particularly in low-resource settings with limited access to renal replacement therapy. We aimed to evaluate the effects of HIV infection on continuous ambulatory peritoneal dialysis (CAPD)-associated peritonitis outcomes and(More)
In this study, a Box Behnken Design (BBD) and a Binary Logistic Regression (BLR) were applied to study the effects of demographic characteristics on the risk of HIV in South Africa. The demographic characteristics studied for each pregnant mother attending an antenatal clinic in South Africa, were mother’s age, partner’s age (father’s age), mother’s level(More)