Wieslaw Paja

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Transcriptional regulation in multi-cellular organisms is a complex process involving multiple modular regulatory elements for each gene. Building whole-genome models of transcriptional networks requires mapping all relevant enhancers and then linking them to target genes. Previous methods of enhancer identification based either on sequence information or(More)
Classification of voice signals in a time domain for detecting some disturbances can be made through mining unique episodes in temporal information systems. In ideal case, a voice signal is periodic and signal shapes in each period are the same. In case of larynx diseases, some disturbances in a voice signal can be distinguished. Selected time windows(More)
Feature selection methods, as a preprocessing step to machine learning , are effective in reducing dimensionality, removing irrelevant data, increasing learning accuracy, and improving result comprehensibility. However, the recent increase of dimensionality of data poses a severe challenge to many existing feature selection methods with respect to the(More)