Wiesław Gołąbek

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The aim of this study was to determine the prevalence of human papillomaviruses (HPV) types 6, 11, 16, 18, 31, 33, 42, 51, 52, 56 and 58 in laryngeal squamous cell carcinoma specimens using immunohistochemical reactions and to correlate the presence of HPV with the clinical and pathological characteristics of these patients. Tissue samples were collected(More)
Human papillomavirus (HPV) is a small DNA virus. HPV is can be divided into two groups: mucosal and cutaneous. HPV have various oncogenic potential. The correlation between presence of high oncogenic type of HPV and carcinogenesis was confirmed in human anogenital tract and cervical carcinoma. The latest studies suggest HPV infection involvement in benign(More)
Nasopharyngeal angiofibromas occur predominantly in males in their puberty and adolescence; the incidence in other age groups and in women is exceptional. This report describes a case of a 57-year-old woman with nasopharyngeal angiofibroma presenting typical radiological findings in computed tomography, MR imaging and angiography. The tumour was(More)
CONCLUSION Contrary to most reports, our study shows that the expression of cyclin D1 is not an independent prognostic factor in patients with laryngeal cancer (LC). No correlation between cyclin D1 expression and survival rates in LC was found in a multivariate analysis. OBJECTIVES The aim of this study was to determine the possible relevance of the(More)
The amount of use of hearing aids was assessed in 190 adults and 22.6% of them used the aid always, 23.7% most of the day, 22.6% every day a little, 20.0% sometimes and 11.1% never. The hearing aids were used more by patients with profound hearing loss than by patients with moderate loss and more by younger and working subjects than by elderly and(More)
Juvenile angiofibroma is a rare, benign, hypervascular, nasopharyngeal tumour. The aim of the study was to assess the value of CT and MR in determining therapeutic approach and follow-up in patients with this condition. There were 40 patients with juvenile angiofibroma. All patients underwent angiography. In 24 patients CT and 5 patients MRI was performed.(More)
BACKGROUND Cholesteatoma of the middle ear or mastoid is a hyperproliferative disorder of keratinocytes characterized by a progressive bone erosion. Matrix metalloproteinase (MMP)-2 and MMP-9 gelatinases are endopeptidases targeting extracellular protein. Several studies examined the role of gelatinases in the pathogenesis of cholesteatoma, but the biologic(More)
UNLABELLED Otosclerosis causes loss of air conduction (AC) but also bone conduction (BC) may be deteriorated. It is reported that also BC may improve after surgical treatment of otosclerosis. The investigation was carried out in a group of 50 patients treated due to otosclerosis in our institution. The group included 34 women and 16 men, at the age 24 to 55(More)
The aim of the study was to analyze the incidence of anatomical variations and abnormalities of the facial nerve found during stapedectomy. Specific management in the case of an anomalous course of the facial nerve was also described. A retrospective analysis of clinical records of 316 stapedectomies was carried out in search for facial nerve anomalies. In(More)
In a group of 153 patients, the result of unilateral stapedectomy was evaluated using Glasgow Benefit Plot. Pure tone average at frequencies 0.5; 1; 2; and 3 kHz of operated and non-operated ear were used to distribute patients to pre- and post-operative groups. In 26 (79%) of 33 patients with unilateral hearing loss, bilateral normal hearing was achieved.(More)