Wiek H Gilst

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The (pro)renin-renin receptor [(P)RR] was discovered as an important novel component of the renin-angiotensin system (RAS). The functional significance of (P)RR is widely studied in renal and vascular pathologies and has sparked interest for a potential role in cardiovascular disease. To investigate the role of (P)RR in cardiac pathophysiology, we aimed to(More)
Restenosis after balloon angioplasty is a serious clinical problem arising in cardiology. Restenosis is caused by the induction of uncontrolled proliferation of vascular smooth muscle cells following damage of the endothelial lining of the vessel by balloon dilation. A gene therapy approach may provide the means to control the mechanisms responsible for(More)
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