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Drought tolerance in barley is highly correlated with the expression of two genes: Hordeum vulgare aleurone 1 (HVA1) and stress-responsive gene 6 (SRG6). Though their role in the mechanism of drought response in barley has been confirmed in transgenic plants, the regulation pathways of these genes’ expression have not been sufficiently studied, especially(More)
Strictly controlled and coordinated induction of CBF regulon (a set of genes regulated by CBF proteins) promotes plant freezing tolerance. CBFs regulate the expression of COR genes that confer freezing tolerance. COR14b in barley is one of the effector genes which seems to be important in resistance to combined freezing and photoinhibition of(More)
BACKGROUND Histamine is a key immunoregulatory mediator and can dampen proinflammatory responses via activation of histamine receptor 2 (H2 R). The aim of this study was to determine the role of H2 R in modulating lung inflammatory responses. METHODS H2 R was blocked using famotidine or activated using dimaprit in both the ovalbumin (OVA) and house dust(More)
BACKGROUND Recently, the nature of the lipid-ligand of Pru p 3, one of the most common plant food allergens in southern Europe, has been identified as a derivative of the alkaloid camptothecin bound to phytosphingosine. However, the origin of its immunological activity is still unknown. OBJECTIVE We sought to evaluate the role of the Pru p 3 lipid-ligand(More)
BACKGROUND Childhood exposure to a farm environment has been shown to protect against the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease. OBJECTIVE We sought to investigate whether both exposure to microbes and exposure to structures of nonmicrobial origin, such as the sialic acid N-glycolylneuraminic acid(More)
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