Werner Mohl

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Thomas Aschacher1
T A At1
Thomas Ac Aschacher@meduniwien1
1Thomas Aschacher
1T A At
1Thomas Ac Aschacher@meduniwien
1Alem Jusic
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Cardiac regeneration remains a clinical target regardless of numerous therapeutic concepts. We formulated a hypothesis claiming that periodic coronary venous pressure elevation (PICSO; Pressure controlled Intermittent Coronary Sinus Occlusion) initiates embedded, but dormant developmental processes in adult jeopardized hearts. Hemodynamics in the primitive(More)
Pressure controlled intermittent coronary sinus occlusion (PICSO) has been found to substantially salvage ischemic myocardium. By elevating venous pressure two mechanisms are involved namely the distention of venous vessels inducing mechanotransduction as well as a redistribution of venous flow towards ischemic areas. Mechanotransduction in endothelial(More)
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