Learn More
Many posttranslational modifications (N-myristoylation or glycosylphosphatidylinositol (GPI) lipid anchoring) and localization signals (the peroxisomal targeting signal PTS1) are encoded in short, partly compositionally biased regions at the N- or C-terminus of the protein sequence. These sequence signals are not well defined in terms of amino acid type(More)
Tandem mass spectrometry (MS/MS) has become a standard method for protein identification in biological samples, but in large-scale proteomics studies, the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, less than 1% of the spectra per sample and about 10% of the peaks per(More)
  • 1