Werner Fischer

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We have recently shown that highly purified lipoteichoic acid (LTA) represents a major immunostimulatory principle of Staphylococcus aureus. In order to test whether this translates to other bacterial species, we extracted and purified LTA from 12 laboratory-grown species. All LTA induced the release of TNF-alpha, IL-1beta, IL-6 and IL-10 in human whole(More)
The primary attachment to polymer surfaces followed by accumulation in multilayered cell clusters leads to biofilm production of Staphylococcus epidermidis, which is thought to contribute to virulence in biomaterial-related infections. We purified a specific polysaccharide antigen of biofilm-producing S. epidermidis 1457 and RP62A, which was recently shown(More)
A detailed mathematical proof is given that the energy spectrum of a quantum particle in multi-dimensional Euclidean space under the influence of certain random potentials is pure point at sufficiently low energies. The results apply in particular to an important class of Gaussian random potentials, which are homogeneous with respect to Euclidean(More)
All homogeneous sphere packings with triclinic symmetry have been derived by studying the characteristic Wyckoff positions P -1 1a and P -1 2i of the two triclinic lattice complexes. These sphere packings belong to 30 different types. Only one type exists that has exclusively triclinic sphere packings and no higher-symmetry ones. The inherent symmetry of(More)
All homogeneous sphere packings and all interpenetrating layers of spheres were derived that refer to the 22 orthorhombic bivariant lattice complexes. In total, sphere packings of 90 different types have been found. Only for 47 of these types is the maximal inherent symmetry of their sphere packings orthorhombic. Some examples demonstrate the usefulness of(More)
For some types of sphere packing with typical one- and two-dimensional parameter regions, the sphere-packing density as a function of the free parameters is discussed. In addition, some sphere-packing types with extraordinary density properties are presented. Until now, it was generally assumed that sphere packings with minimal density are also those of(More)
Load commutated inverters (LCI) cover a large variety of industry applications in a power range up to 100 MW. The paper discusses realized applications in power generation, oil and gas, marine drives, and metal industry. A new LCI family with a high grade of modularity allows covering all these applications with a minimum of different parts. The heart of(More)
The functional–analytic versus the functional–integral approach to quantum Hamiltonians: The one–dimensional hydrogen atom * Abstract The capabilities of the functional–analytic and of the functional–integral approach for the construction of the Hamiltonian as a self–adjoint operator on Hilbert space are compared in the context of non–relativistic quantum(More)