APP-BP1, first identified as an amyloid precursor protein (APP) binding protein, is the regulatory subunit of the activating enzyme for the small ubiquitin-like protein NEDD8. We have shown that APP-BP1 drives the S- to M-phase transition in dividing cells, and causes apoptosis in neurons. We now demonstrate that APP-BP1 binds to the COOH-terminal 31 amino… (More)
APP-BP1, first identified as a protein that interacts with the carboxyl (C) terminus of the amyloid precursor protein (APP), is one-half of the bipartite activating enzyme for the ubiquitin-like protein NEDD8. We report here that APP-BP1 also specifically interacts with apoptosis stimulating protein of p53 ASPP2 in non-transfected cells through the… (More)
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BACKGROUND Bacterial meningitis is a serious infection in children and adults worldwide, with considerable morbidity, mortality, and severe neurological sequelae. Dexamethasone is often used before antibiotics in cases of this disease, and improves outcomes. OBJECTIVE Although several studies have identified the role of adjunctive dexamethasone therapy in… (More)
VoiceXML is a language of the W3C to create voice-user interfaces, particularly for the telephone. This paper first shows the importance of voice interface to M-commerce, then presents the VoiceXML techniques and a certain business applications on M-commerce. At last, we draw some conclusions.
Widely review all kinds of current travel-service & information systems, we will find there’re a great many disadvantages in them and most important, various systems are difficult to be integrated, so they are in a separate state. Web Service is a newest communicating and integrating technique on Internet. This paper briefly introduces Web… (More)
VoiceXML (Voice eXtensible Markup Language) is a language of the W3C to create voice-user interfaces, particularly for the telephone. It uses speech recognition and touchtone (DTMF keypad) for input, and pre-recorded audio and text-to-speech synthesis (TTS) for output. The text-to-speech synthesis feature opens new perspectives for e-commerce. We are no… (More)
E-government is one of the major forms of government informatization. It has played an important role in the rural areas of some Asian countries. This article gives an analysis of e-government application in some rural areas in Asia and the status of e-government application in rural China, and gets some enlightenment to solve our problems. First, Japan… (More)