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OBJECTIVES The objective of this study was to determine the association of 19 mutations with frequencies ≥ 10% in the core promoter region of hepatitis B virus (HBV) with chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular carcinoma (HCC). METHODS Eight hundred forty-six asymptomatic hepatitis B surface antigen carriers (ASCs), 235 CHB(More)
The associations of nucleotide substitution mutations in the preS region of hepatitis B virus (HBV) with hepatocellular carcinoma (HCC) and cirrhosis remain unknown. We aimed to determine the associations of preS mutations with HCC or cirrhosis. HBV from 603 asymptomatic hepatitis B surface antigen carriers (ASCs), 219 chronic hepatitis B (CHB) patients,(More)
BACKGROUND The X-ray cross-complementing group 3 (XRCC3) gene encodes a protein that plays an important role in homologous recombination repair (HRR) of DNA double-strand break (DSB). Increasing attention has been drawn to the association of XRCC3 T241M polymorphism with various types of human cancers. In this study, a meta-analysis was performed to(More)
BACKGROUND Bladder cancer is of compelling morbidity and mortality due to its high recurrence rate. Little development has been made in the last decades in the therapy methods. Thus, the mechanism of its growth and invasiveness involving novel molecular targets are needed. OBJECTIVE Our research objective is to confirm the hypothesis that miR-1-3p(More)
We attempted to analyze the effects of miR-1-3p and CCL2 on the proliferation, migration, and invasion of bladder cancer cells. A total of 18 pairs of bladder cancer tissues with corresponding adjacent tissues and the 6 cases of normal tissues were collected. The expressions of miR-1-3p and CCL2 in the cancer tissues were evaluated using quantitative(More)
OBJECTIVE To compare the levels of the fasting blood glucose (FBG) and blood fat of the patients with obstructive sleep apnea hypopnea syndrome (OSAHS) before and after surgery, meanwhile to analyze the influence on blood glucose and blood fat after the changes of body mass index (BMI), apnea-hypopnea index (AHI) and lowest oxygen saturation (LSpO2). (More)
OBJECTIVE To discuss the changes of the auditory brain stem response in patients with Ramsay Hunt syndrome. METHOD Thirty-six patients of Ramsay Hunt syndrome,who have only unilateral involvement with contralateral good ear, were studied with pure tone test and auditory brain stem response. The latencies of peaks I, III and V and interpeak latencies of(More)
OBJECTIVE To explore early post-operative complications following surgery for chronic suppurative otitis media. METHOD From Jan 1992 to July 2000, 291 cases of chronic suppurative otitis media have been treated in our department. 79 cases underwent myringoplasty, 82 cases tympanoplasty, 88 cases modified radical mastoidectomy and 42 cases radical(More)
OBJECTIVE To provide anatomic basis for genioglossus advancement. METHOD Forty adult cadaver heads (male=29, female=11) were dissected to measure genial tubercles and observe the start-stop points of genioglossus muscle and geniohyoid muscle. RESULT The genioglossus muscle originates from the superior mental spine, and the geniohyoid muscle originates(More)
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