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α-Glucosidase inhibitors isolated from medicinal plants
Abstract Objective α -Glucosidase inhibitors can be used as a new class of antidiabetic drug. By competitively inhibiting glycosidase activity, these inhibitors help to prevent the fast breakdown ofExpand
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Antioxidant and a-glucosidase inhibitory activity of red raspberry (Harrywaters) fruits in vitro
[2,2-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid] Diammonium salt (ABTS) radical scavenging and ferric reducing antioxidant power (FRAP) assay were used to analyze the antioxidant activity ofExpand
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α-glucosidase inhibitory in vitro and antidiabetic activity in vivo of Osmanthus fragrans
In this study, EtOAC extract of Osmanthus fragrans were evaluated by a-glucosidase inhibitory activity in in-vitro, and showed stronger inhibiting activity of a-glucosidase (IC50=12.5 μg/ml) comparedExpand
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[Alpha-glucosidase inhibitors from leaves of Forsythia suspense in Henan province].
OBJECTIVE The alpha-glucosidase inhibitory compounds were searched from Forsythia suspense. METHOD The active compounds were isolated by the method of bioassay-guided in vitro and columnExpand
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Effects and mechanisms of iridoid glycosides from Patrinia scabiosaefolia on improving insulin resistance in 3T3-L1 adipocytes.
Insulin resistance causes several adverse effects such as hypertension, diabetes and different aspects of cardiovascular diseases. Patrinia scabiosaefolia Fisch. ex Trev. is a traditional ChineseExpand
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Inhibitory activity of Euphorbia humifusa for α-glucosidase in vitro and in vivo
Euphorbia humifusa belongs to the Euphorbiaceae family and is widely distributed in China [1]. E. humifusa is an important traditional Chinese medicine used under the names Qingrejiedu,Expand
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Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based extraction
Ionic liquid 1-butyl-3-methylimidazolium bromide-methanol-based ultrasonic-assisted extraction (ILUAE) was used to extract tilianin and acacetin from the aerial parts of Agastache rugose (A. rugose),Expand
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Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway
Here we provide evidences to link cystathionine-γ-lyase (CSE) to the development of breast cancer. CSE expression is up-regulated in both breast cancers and breast cancer cell lines and results inExpand
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In vitro antioxidant properties and in vivo lowering blood lipid of Forsythiasuspense leaves
The active compounds from Forsythia suspense were screened for antioxidant activities in vitro and lowering blood lipid and lipid peroxidation in vivo. Five compounds, ursolic acid, phillygenin,Expand
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Antithrombotic components of Malus halliana Koehne flowers.
Flowers of Malus halliana (M. halliana) Koehne have been used as a Chinese traditional medicine to treat metrorrhagia and in our study, its chemical composition and anticoagulant effect wereExpand
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