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miR-30 Family Reduction Maintains Self-Renewal and Promotes Tumorigenesis in NSCLC-Initiating Cells by Targeting Oncogene TM4SF1.
  • Yushui Ma, Fei Yu, D. Fu
  • Biology, Chemistry
    Molecular therapy : the journal of the American…
  • 1 December 2018
Reduced hsa-miR-124-3p levels are associated with the poor survival of patients with hepatocellular carcinoma
TLDR
It is demonstrated that hsa-miR-124-3p might be a potential target for the diagnosis and prognosis of HCC, and lower hsa/miR/ subtitle expression was shown to be correlated with a shorter OS and poor prognosis in HCC.
Expression and potential prognostic value of histone family gene signature in breast cancer
TLDR
Higher expression of histone gene sets was associated with poor overall survival, relapse- free survival and distant metastasis-free survival of BC patients, indicating that histone family genes sets may be used as prognostic factors for survival prediction for BC patients.
Prognostic implications of decreased microRNA-101-3p expression in patients with non-small cell lung cancer
TLDR
Survival analysis through univariate and multivariate models indicated that the miR-101-3p expression level was a crucial risk factor for OS and DFS in patients with NSCLC, and indicated that miR -101- 3p may serve as a biomarker for patients withNSCLC who have received adjuvant chemotherapy.
MicroRNA‑mRNA integrated analysis based on a case of well‑differentiated thyroid cancer with both metastasis and metastatic recurrence.
TLDR
The integrated analysis with TCGA data indicated several prognostic markers and regulatory networks for potential treatment and provided possible molecular mechanisms in which the ribosome and p53 pathways may respectively contribute to bone metastasis and local recurrence of metastasis.