Learn More
BACKGROUND In human oocytes, as in other mammalian ova, there is a significant variation in the pregnancy potential, with approximately 20% of oocyte-sperm meetings resulting in pregnancies. This frequency of successful fertilization decreases as the oocytes age. This low proportion of fruitful couplings appears to be influenced by changes in mitochondrial(More)
Our initial in vitro (HL-60 cells) and in vivo (B16-F10 murine) studies showed nanosecond pulsed electric fields (nsPEFs) caused intracellular changes and melanoma involution, respectively. We wanted to describe the morphologic changes in cell ultrastructure and investigate the mechanism for change due to nsPEFs in B16-F10 melanoma tumors in SKH-1 mice. We(More)
The submandibular glands of male mice contain epidermal growth factor (EGF) and other growth factors that have tropic and mitogenic properties (Byyny et al., 1972; Carpenter & Cohen, 1979). EGF increases the incorporation of thymidine into DNA of the mouse gastrointestinal tract (Scheving et al., 1980) and stimulates ornithine decarboxylase activity in(More)
  • 1