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We have investigated human male demographic history using 590 males from 51 populations in the Human Genome Diversity Project - Centre d'Etude du Polymorphisme Humain worldwide panel, typed with 37 Y-chromosomal Single Nucleotide Polymorphisms and 65 Y-chromosomal Short Tandem Repeats and analyzed with the program Bayesian Analysis of Trees With Internal(More)
To investigate the association between alcohol consumption and multiple sclerosis risk, we performed a systematic literature search of PubMed, EmBase and Web of Science databases for all relevant articles regarding alcohol and multiple sclerosis. Our meta-analysis consisted of 10 studies, including nine case-controls and one cohort study. The odds ratios(More)
In this paper, we propose a robust sparse spectrum fitting method (RSpSF) for Directions-Of-Arrival (DOA) and power estimation in the presence of general form of modeling errors in the array manifold matrix. By exploiting the group sparsity between the power spectrum and the modeling errors, RSpSF formulates the estimator as a convex optimization program.(More)
The mammalian central nervous system (CNS) relies on a constant supply of external glucose for its undisturbed operation. This article presents an implantable Multi-Electrode Array (MEA) probe for brain glucose measurement. The MEA was implemented on Silicon-On-Insulator (SOI) wafer using Micro-Electro-Mechanical-Systems (MEMS) methods. There were 16(More)
—Maximum Likelihood estimator (ML) has shown excellent performance of Direction Of Arrival (DOA) estimation in Multiple Input Multiple Output (MIMO) array. However, the computation burden of MIMO ML is very large. In order to resolve this problem, a novel MIMO Maximum Likelihood DOA Estimation based on Metropolis-Hasting Sampling (MIMO MHML) is proposed,(More)
Dopa-responsive dystonia (DRD) is a rare inherited dystonia that responds very well to levodopa treatment. Genetic mutations of GTP cyclohydrolase I (GCH1) or tyrosine hydroxylase (TH) are disease-causing mutations in DRD. To evaluate the genotype-phenotype correlations and diagnostic values of GCH1 and TH mutation screening in DRD patients, we carried out(More)
To study associations between type 2 diabetes (T2DM) candidate genes and microvascular complications of diabetes (MVCDs), we performed case-control association studies for both T2DM and MVCDs in Han Chinese subjects. We recruited 1,939 unrelated Han Chinese T2DM patients and 918 individuals with normal blood glucose levels as nondiabetic controls. Among(More)
Unlike genetic aberrations, epigenetic alterations do not modify the deoxyribonucleic acid (DNA) coding sequence and can be reversed pharmacologically. Identifying a particular epigenetic alteration such as abnormal DNA methylation may provide better understanding of cancers and improve current therapy. In a Chinese pedigree with colorectal carcinoma and(More)
The single-carrier block transmission (SCBT) method has been considered for bandwidth efficiency in underwater acoustic (UWA) communication recently. The cyclic prefix (CP) in the SCBT method should be longer than the multipath spread, but a long CP reduces the data rate of SCBT UWA communications in significant multipath channels. The proposed scheme in(More)
The problem of direction of arrival (DOA) for multiple-input multiple-output (MIMO) array systems is considered, where orthogonal waveforms are transmitted simultaneously. A novel DOA estimation algorithm for collocated MIMO array is proposed. The proposed algorithm exploits the time delay to obtain two cross-correlation matrices, where the effect of(More)