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S-Adenosylmethionine (SAM) plays a crucial role as a methyl donor in various biological processes and has been previously shown to be involved in adipogenesis in skeletal muscle. This study was conducted to explore the mechanism of SAM inducing adipogenesis in skeletal muscle. Adipose precursor cells, 3T3-L1, and C2C12 cells, were induced into adipogenic(More)
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cells (PASMCs) and suppressed apoptosis. Platelet-derived growth factor (PDGF) is a potent mitogen involved in cell proliferation and migration. PDGF-BB induces the proliferation and migration of PASMCs and has(More)
Estrogen withdrawal following menopause results in an increase of osteoclasts formation and bone resorption, which is one of the most important mechanisms of postmenopausal osteoporosis. Recently, growing evidence has suggested that receptor-interacting protein 140 was implicated in estrogen-regulated metabolic disease, including fat metabolism and lipid(More)
Conventional image matching methods hardly consider the location relationships between matching points, reducing the reliability and accuracy of matching results. A novel matching mode based on SIFT (scale-invariant feature transform) keypoints and multi-subregions information is proposed in this paper. The new strategy breaks the isolation between matching(More)
Traditional methods to extract water regions in SAR images usually rely on image binarization with a specified threshold. However, because of the inherent speckles in SAR images, finding an appropriate threshold is very difficult. In the paper, we propose a new method for water region extraction in SAR images using GLCM (gray-level co-occurrence matrix)(More)
BACKGROUND Intervertebral disc degeneration (IDD) has been widely recognized as a major contributor to low back pain. Accumulating evidence suggests that IDD is linked to various pro-inflammatory cytokines and metabolites. Recently, numerous studies have demonstrated that microRNAs (miRNAs) play a pivotal role in the development of most disorders, including(More)
The estimated accuracy of phase and frequency of all phase FFT spectrum analysis and its correction techniques are high[1-3], for its perfect characteristic of inhibiting the spectrum leakage. The phase isn't influenced by frequency shift, so there is no need to correct it. In this paper, a spectrum analyzer with self-adaptive sampling frequency is designed(More)
Coastline detection in synthetic aperture radar (SAR) images is difficult and important. As we all know, water areas in SAR images are much more homogeneous in grey levels than land regions. Therefore, features reflecting the texture of an image can be very useful for water-land separation. Traditional methods mainly view gray-scale as a critical rule to(More)