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The aim of this study was to test the hypothesis that gastric lavage with soybean isoflavone activates the Notch signaling pathway and prevents apoptosis in the cerebral cortex during experimental strokes. Sprague-Dawley rats were randomly assigned to four groups of 10 rats each: sham operation plus vehicle (Sham), middle cerebral artery occlusion plus(More)
Toll-like receptors (TLR) have a critical role in innate immunity against pathogens. We investigated the cytokine response to TLR stimulation in peripheral blood cells of subjects infected with hepatitis C virus (HCV) and/or human immunodeficiency virus (HIV) in the Women Interagency HIV Study (WIHS) cohort. Interleukin (IL)-6 in response to TLR3 and TLR4(More)
The aim of the current study was to explore mechanisms of SEMA3B gene expression and its clinical significance in glioma, and provide a theoretical foundation for investigating individualized treatment in glioma. Paraffin-embedded tissues from 43 patients with a confirmed clinical diagnosis of glioma following neurosurgery at the First Affiliated Hospital(More)
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