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This study aims to quantify the effects of topographic variability (measured by coefficient variation of elevation, CV) and lidar (Light Detection and Ranging) sampling density on the DEM (Digital Elevation Model) accuracy derived from several interpolation methods at different spatial resolutions. Interpolation methods include natural neighbor (NN),(More)
—In remote-sensing classification, there are situations when users are only interested in classifying one specific land-cover type, without considering other classes. These situations are referred to as one-class classification. Traditional supervised learning is inefficient for one-class classification because it requires all classes that occur in the(More)
Light detection and ranging (lidar) data is increasingly being used for ecosystem monitoring across geographic scales. This work concentrates on delineating individual trees in topographically-complex, mixed conifer forest across the California's Sierra Nevada. We delineated individual trees using vector data and a 3D lidar point cloud segmentation(More)
Tau is a microtubule-associated protein that promotes microtubule assembly and stability. In Alzheimer's disease and related tauopathies, tau fibrillizes and aggregates into neurofibrillary tangles. Recently, oleocanthal isolated from extra virgin olive oil was found to display non-steroidal anti-inflammatory activity similar to ibuprofen. As our(More)
This paper studies a variant of the three-dimensional bin packing problem (3D-BPP), where the bin height can be adjusted to the cartons it packs. The bins and cartons to be packed are assumed rectangular in shape. The cartons are allowed to be rotated into any one of the six positions that keep the carton edges parallel to the bin edges. This greatly(More)
Tau proteins are building blocks of the filaments that form neurofibrillary tangles of Alzheimer's disease (AD) and related neurodegenerative tauopathies. It was recently reported that two VQIXXK motifs in the microtubule (MT) binding region, named PHF6 and PHF6*, are responsible for tau fibrillization. However, the exact role each of these motifs plays in(More)