Share This Author
Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis.
Therapeutic effects of higenamine combined with ‐gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function
- Jianxia Wen, Lu Zhang, Yanling Zhao
- Biology, ChemistryJournal of cellular and molecular medicine
- 19 February 2020
The present work demonstrates that HG/‐GR prevented DOX‐induced cardiotoxicity via the cardiotonic effect and promoting myocardial energy metabolism through the LKB1/AMPKα/Sirt1 signalling pathway, which promotes mitochondrial energy metabolism and protects against CHF.
Di’ao Xinxuekang Capsule, a Chinese Medicinal Product, Decreases Serum Lipids Levels in High-Fat Diet-Fed ApoE–/– Mice by Downregulating PCSK9
- Liping Qu, Didi Li, Xiaoping Gao, Yongwei Li, Jianming Wu, Wenjun Zou
- BiologyFrontiers in Pharmacology
- 1 November 2018
This study is the first to show that DXXK could alleviate lipid disorder and ameliorate atherosclerosis with downregulation of the PCSK9 in high-fat diet-fed ApoE–/– mice, suggesting that D XXK may be a potential novel therapeutic treatment and may support statin action in the treatment of atherosclerotic cardiovascular disease.
Two Ellagic Acids Isolated from Roots of Sanguisorba officinalis L. Promote Hematopoietic Progenitor Cell Proliferation and Megakaryocyte Differentiation
A class of small molecules which differ from others non-peptidyl, and appears to have potential for clinical development as a therapeutic agent for patients with blood platelet disorders, is reported to induce megakaryopoiesis.
Elucidation of the molecular mechanism of Sanguisorba Officinalis L. against leukopenia based on network pharmacology.
Efficacy and Safety of Avatrombopag in Patients With Thrombocytopenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A meta-analysis showed that avatrombopag was an effective treatment for thrombocytopenia, but there is sufficient evidence to indicate that adverse events may occur.
Clinical Efficacy and Safety of Eight Traditional Chinese Medicine Combined with Entecavir in the Treatment of Chronic Hepatitis B Liver Fibrosis in Adults: A Network Meta-Analysis
For improving the HBV-DNA negative conversion rates, adding TCM to the therapeutic strategies does not seem to show absolute superiority, and FHC combined with entecavir is the best therapeutic strategy.
Cardioprotective effects of Aconiti Lateralis Radix Praeparata combined with Zingiberis Rhizoma on doxorubicin-induced chronic heart failure in rats and potential mechanisms.
Dioscin and diosgenin: insights into their potential protective effects in cardiac diseases.