Wenjuan Cui

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Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation in human DNA. The sequence of SNPs in each of the two copies of a given chromosome in a diploid organism is referred to as a haplotype. Haplotype information has many applications such as gene disease diagnoses, drug design, etc. The haplotype assembly problem is defined as(More)
Linkage analysis is the first step in the search for a disease gene. Linkage studies have facilitated the identification of several hundred human genes that can harbor mutations leading to a disease phenotype. In this paper, we study a very important case, where the sampled individuals are closely related, but the pedigree is not given. This situation(More)
The unconventional emergency, such as massive natural disaster, public health, food safety and social security incident, usually outbreak more suddenly, diffused more quickly, cause more secondary damage and derive more disaster and with fewer omens exceeding what it is expected. It needs a large number of environmental, social and economic development data(More)