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BACKGROUND HIV-related opportunistic infections (OIs) and malignancies continued to cause morbidity and mortality in Chinese HIV-infected individuals. The objective for this study is to elucidate the prevalence and spectrums of OIs and malignancies in HIV-infected patients in the Beijing Ditan Hospital. METHODS The evaluation of the prevalence and(More)
We identified the Rho GTPase Rnd1 as a candidate metastasis suppressor in basal-like and triple-negative breast cancer through bioinformatics analysis. Depletion of Rnd1 disrupted epithelial adhesion and polarity, induced epithelial-to-mesenchymal transition, and cooperated with deregulated expression of c-Myc or loss of p53 to cause neoplastic conversion.(More)
Hypoxia-inducible factor 1 alpha (HIF-1α) is closely related with chemoresistance of solid tumors. The purpose of this study was to investigate the ability of noscapine to inhibit HIF-1α and sensitize ovarian cancer cells to cisplatin (DDP) under hypoxic conditions. Herein, we report that noscapine sensitized cobalt-induced chemoresistant ovarian cancer(More)
Inkjet printing and additive manufacturing technologies (AMT) are introduced for the fabrication of flexible RF/microwave electronics and sensors. ABSTRACT | Inkjet printing on flexible paper and additive manufacturing technologies (AMT) are introduced for the sustainable ultra-low-cost fabrication of flexible radio frequency (RF)/microwave electronics and(More)
Due to the lack of a general theoretical foundation, today's distributed traffic control mechanisms developed at the networking layer, transport layer, and overlay are largely disintegrated. As a result, traffic control protocols developed at different layers may achieve conflicting design objectives and interact with one another in an unpredictable(More)
Conductance quantization phenomena are observed in oxide-based resistive switching memories. These phenomena can be understood by the formation and disruption of atomic-scale conductive filaments in the insulating oxide matrix. The quantum conductance effect can be artificially modulated by controlling the electrical parameters in Set and Reset processes,(More)
In this paper, we present an automatic artifact removal method by combining independent component analysis (ICA) and wavelet denoising to remove artifacts from attention deficit hyperactivity disorder (ADHD) electroencephalograms (EEGs). First, the ICA algorithm is used to analyze EEG signals to get the independent components (ICs); then, the wavelet method(More)
The precise formation of three-dimensional motor circuits is essential for movement control. Within these circuits, motoneurons (MNs) are specified from spinal progenitors by dorsoventral signals and distinct transcriptional programs. Different MN subpopulations have stereotypic cell body positions and show specific spatial axon trajectories. Our knowledge(More)
BACKGROUND The downregulation of the tumor suppressor miR200c plays important roles in many malignant tumors. This study aims to show that miR200c is a posttranscriptional regulator of insulin receptor substrate 1 (IRS1) and over-expression of miR200c suppresses prostate cancer cell growth. METHODS Bioinformatics analysis was used to show potential(More)