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Neovasculogenesis induced by stem cell therapy is an innovative approach to improve critical limb ischemia (CLI) in diabetes. Mesenchymal stem cells (MSCs) are ideal candidates due to their angiogenic and immunomodulatory features. The aim of this study is to determine the therapeutic effects of human placenta-derived MSCs (P-MSCs) on diabetic CLI, with or(More)
Mesenchymal stem cells (MSCs) represent a heterogeneous cell population that is promising for regenerative medicine. The present study was designed to assess whether VCAM-1 can be used as a marker of MSC subpopulation with superior angiogenic potential. MSCs were isolated from placenta chorionic villi (CV). The VCAM-1+/− CV-MSCs population were separated by(More)
Lipocalin 2 (LCN2), a multifunctional secretory protein known as neutrophil gelatinase-associated lipocalin (NGAL), is expressed in a variety of cancers. However, little is known about the biological functions of NGAL in the development of lung adenocarcinoma. In the present study, we primarily found that NGAL expression was up-regulated in human lung(More)
The aim of this study was to analyze Surface Electromyography (sEMG) of low back muscles of low back pain (LBP) patients when they performed different movements. We recruited eighteen female LBP patients and eighteen healthy female subjects. They performed forward and backward trunk bending with the maximum voluntary movement, while sEMG data were collected(More)
This paper estimates the benefits of the motorized seat belt in ADAS in both safety and economic aspects. The motorized seat belt could reduce the forward displacement of occupants during brake, which could result in more severe injuries in frontal crashes. A MADYMO model is used to simulate the forward displacement of the driver during brake. Sled tests(More)
Human umbilical cord mesenchymal stromal cells (hUC-MSCs) are currently being used as novel therapeutic agents in numerous clinical trials. Previous works have shown that hUC-MSCs possess profound immunomodulatory capacities through IL-1 stimulation produced by peripheral blood mononuclear cells (PBMCs), their main cellular partner in most(More)
All-trans retinoic acid (ATRA) induces clinical remission in most acute promyelocytic leukemia (APL) patients by inducing terminal differentiation of APL cells toward mature granulocytes. Here we report that human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are capable of inducing granulocytic differentiation of the APL-derived NB4 cell line as(More)
The aim of this study was to analyse quantitatively spine angle changes of subjects suffering from low back pain (LBP) during dynamic exercises. We explored the differences in the range of spine angle based on gender, disability severity, the correlation between the spine angle range and the visual analogue scale (VAS) scores, as well as the differences in(More)
Numerous studies have demonstrated that interferon-γ (IFN-γ) is an important inflammatory cytokine, which may activate the immunomodulatory abilities of mesenchymal stem cells (MSCs), and may influence certain other functions of these cells. MicroRNAs are small non‑coding RNAs that regulate the majority of the biological functions of cells and are important(More)