Wenjie Yuan

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In the yeast Saccharomyces cerevisiae the TOR complex 1 (TORC1) controls many growth-related cellular processes and is essential for cell growth and proliferation. Macrolide antibiotic rapamycin, in complex with a cytosol protein named FKBP12, specifically inhibits TORC1, causing growth arrest. The FKBP12-rapamycin complex interferes with TORC1 function by(More)
BACKGROUND Ethanol production from non-crop materials, such as Jerusalem artichokes, would make a great contribution to the energy industry. The non-conventional yeast, Kluyveromyces marxianus, is able to carry out ethanol fermentation of sugar molecules obtained from inulin-containing materials by consolidated bioprocessing. Lower inulin concentrations and(More)
Ethanol fermentation from Jerusalem artichoke tubers by recombinant Saccharomyces cerevisiae strains expressing the inulinase gene (inu) from Kluyveromyces marxianus was investigated. The inu native and pgk promoters were used to drive the expression of the inu gene, and the inulinase was expressed as an extracellular enzyme. All positive clones (confirmed(More)
Besides topological relations and approximate relations, cardinal directions have turned out to be an important class of qualitative spatial relations. In spatial databases and GIS they are frequently used as selection criteria in spatial queries. But the available models of cardinal relations suffer from a number of problems like the unequal treatment of(More)
Besides topological relationships and approximate relationships, <i>cardinal directions</i> like <i>north</i> and <i>southwest</i> have turned out to be an important class of qualitative spatial relationships. They are of interdisciplinary interest in fields like cognitive science, robotics, artificial intelligence, and qualitative spatial reasoning. In(More)
People may have problems in finding their way to destinations in large buildings. This raises a need of designing and constructing indoor navigation systems. However, none of the available indoor navigation models can automatically calculate shortest paths according to the geometric structure of indoor space. The reasons are that those models which use(More)
With the prevalence of car navigation systems, indoor navigation systems are increasingly attracting attention in the indoor research area. However, the available models for indoor navigation suffer from the problems that architectural constraints are not considered, route planning is only based on 2D planes, users are represented as points without(More)
Range query processing is an important technology in spatial databases. Current studies mainly focus on range queries in outdoor space based on the Euclidean or network distances, but rarely any approach is proposed for indoor space. In this paper, we present two network-based approaches to supporting stationary range queries and continuous range queries(More)
Biobutanol outperforms bioethanol as an advanced biofuel, but is not economically competitive in terms of its titer, yield and productivity associated with feedstocks and energy cost. In this work, the synergistic effect of calcium and zinc was investigated in the acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum using glucose, xylose(More)
Gelatin contains many functional motifs which can modulate cell specific adhesion, so we modified polycarbonate urethane (PCU) scaffold surface by immobilization of gelatin. PCU-g-gelatin scaffolds were prepared by direct immobilizing gelatins onto the surface of aminated PCU scaffolds. To increase the immobilization amount of gelatin, poly(ethylene glycol)(More)