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We examined whether Siglec-9 modulates cytokine production in the macrophage cell line RAW264. Cells expressing Siglec-9 produced low levels of tumor necrosis factor (TNF)-alpha upon stimulation with lipopolysaccharide, peptidoglycan, unmethylated CpG DNA, and double-stranded RNA. On the other hand, interleukin (IL)-10 production was strongly enhanced in(More)
Web application modeling and implementation method are related with middleware platform tightly, and its models usually can’t be reused on different platform. In order to reuse web application models, it is necessary to raise the level of abstraction of models, constructing middleware platform independent models. Roles are meant to capture observable(More)
Siglecs are immunoglobulin lectin group proteins that recognize the sialic acid moiety. We previously reported that the expression of Siglec-9 on the macrophage cell line RAW264 markedly enhanced Toll-like receptor (TLR)-induced interleukin (IL)-10 production and inhibited the production of proinflammatory cytokines. In this study, we examined the(More)
Bridging pattern refers to the separation of the abstract section and implementation section. Using this pattern these sections can changing independently. So this design pattern can be well used in information system. This paper take a information system for example in order to show how to use this pattern in information system, and the advantages of(More)
This paper examines the impact of foreign ownership on stock return volatility in China A stock markets. Foreign investors will be divided into two categories, we show that mutual fund ownership is negatively related to stock return volatility. We also demonstrate that the measures of foreign ownership in this paper differ substantially from the measure(More)
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