Wenji Li

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PURPOSE The aim of this study was to develop sucrose ester (SE)-stabilized oleanolic acid (OA) nanosuspensions (NS) for enhanced delivery. METHODS SEOA NS were prepared via O/W emulsion and organic solvent evaporation methods. The particles' size and polydispersity index were measured by nanosizer. Their percent encapsulation efficiency, saturation(More)
The effects of polyethylene glycol 20000 (PEG 20000) on the intestinal absorption of prednisolone, methylprednisolone and quinidine, three P-glycoprotein (P-gp) substrates, across the isolated rat intestinal membranes were examined by an in-vitro diffusion chamber system. The serosal-to-mucosal (secretory) transport of these P-gp substrates was greater than(More)
As most Web sites are designed for desktop PCs, it is extremely uncomfortable to browse these large pages on a mobile handheld device with small screen and limited user interface. By referring to thumbnail view concept, VIPS (vision based page segmentation) method and AJAX, which is core technology of web2.0, a dynamic Web page adaptation for mobile device(More)
In the present study, the effect of a borneol/menthol eutectic mixture (25:75) and microemulsion on the absorption of daidzein in rat intestinal membrane was evaluated. The microemulsion formulation was composed of ethyl oleate (oil), Cremophor RH40 (surfactant), PEG400 (co-surfactant), and water. The borneol/menthol eutectic mixture and its microemulsion(More)
Flash caching has emerged as a promising solution to the scalability problems of storage systems by using fast flash memory devices as the cache for slower primary storage. But its adoption faces serious obstacles due to the limited capacity and endurance of flash devices. This paper presents CacheDedup, a solution that addresses these limitations using(More)
In mobile computing environments, as handheld devicespsila small-screen, limited computing ability and capacity of storage, consumers still experience difficulties when browsing the Web on such devices. Some researches focus on how to adapt a normal Web page to handheld device. Meanwhile, it is necessary to put existing Web adaptation engines into practice.(More)
Young breast cancer occupies a higher and higher proportion of breast cancer, especially in Asia, and is associated with a more unfavorable prognosis compared with the disease arising in older women. However, the poor prognosis of young breast cancer cannot be fully explained by the clinical and molecular factors. This study investigated 1125 Chinese breast(More)
Mobile handheld devices, as small-screen, limited computing ability and capacity of storage, can not browse normal Web page comfortably. A new effective P2P collaborative mode for mobile Web surfing is proposed that mobile users can collaborative browse a normal rich Web page designed for PC. Firstly, a layered Web page adaptation engine is designed for the(More)
—In order to better understand the advantages and disadvantages of a constrained multi-objective evolutionary algorithm (CMOEA), it is important to understand the nature of difficulty of a constrained multi-objective optimization problem (CMOP) that the CMOEA is going to deal with. A CMOP includes objectives and constraints, and a number of features, such(More)
—Through analysis, we point out Luo et al.'s and Sun et al.'s signcryption-based concurrent signature schemes have the same defect in ambiguity and therefore the fair exchange protocols based on their schemes are not fair. Thus based on the notions of signcryption and concurrent signature, a new signcryption-based concurrent signature scheme from bilinear(More)