Wenji Li

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—Automated blood vessel segmentation plays an important role in the diagnosis and treatment of various cardio-vascular and ophthalmologic diseases. In this paper, a novel unsupervised segmentation algorithm is proposed to extract blood vessels from fundus images. At first, an enhanced vessel image is generated by morphological reconstruction, and then(More)
—This paper proposes an improved epsilon constraint handling method embedded in the multi-objective evolutionary algorithm based on decomposition (MOEA/D) to solve constrained multi-objective optimization problems (CMOPs). More specifically, it dynamically adjusts the epsilon level, which is a critical parameter in the epsilon constraint method, according(More)
—In order to better understand the advantages and disadvantages of a constrained multi-objective evolutionary algorithm (CMOEA), it is important to understand the nature of difficulty of a constrained multi-objective optimization problem (CMOP) that the CMOEA is going to deal with. A CMOP includes objectives and constraints, and a number of features, such(More)
Astaxanthin (AST), a red dietary carotenoid, has synergistic antioxidant effects with polyunsaturated fatty acids at low concentrations via Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or Nrf2)/antioxidant response element (ARE) signaling. In addition, chromatin remodeling and DNA methylation-based gene silencing represent a common mechanism in(More)
Flash caching has emerged as a promising solution to the scalability problems of storage systems by using fast flash memory devices as the cache for slower primary storage. But its adoption faces serious obstacles due to the limited capacity and endurance of flash devices. This paper presents CacheDedup, a solution that addresses these limitations using(More)
Young breast cancer occupies a higher and higher proportion of breast cancer, especially in Asia, and is associated with a more unfavorable prognosis compared with the disease arising in older women. However, the poor prognosis of young breast cancer cannot be fully explained by the clinical and molecular factors. This study investigated 1125 Chinese breast(More)
In this paper, we design a set of multi-objective constrained optimization problems (MCOPs) and propose a new repair operator to address them. The proposed repair operator is used to fix the solutions that violate the box constraints. More specifically, it employs a reversed correction strategy that can effectively avoid the population falling into local(More)