Wenji Li

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The firing pattern of auditory neurons is determined in part by the type of voltage-sensitive potassium channels expressed. The expression patterns for two high-threshold potassium channels, Kv3.1 and Kv3.3, that differ in inactivation properties were examined in the rat auditory system. The positive activation voltage and rapid deactivation kinetics of(More)
—In order to better understand the advantages and disadvantages of a constrained multi-objective evolutionary algorithm (CMOEA), it is important to understand the nature of difficulty of a constrained multi-objective optimization problem (CMOP) that the CMOEA is going to deal with. A CMOP includes objectives and constraints, and a number of features, such(More)
In this paper, we design a set of multi-objective constrained optimization problems (MCOPs) and propose a new repair operator to address them. The proposed repair operator is used to fix the solutions that violate the box constraints. More specifically, it employs a reversed correction strategy that can effectively avoid the population falling into local(More)
Aberrant DNA methylation at the 5-carbon on cytosine residues (5mC) in CpG dinucleotides is probably the most extensively characterized epigenetic modification in colon cancer. It has been suggested that the loss of adenomatous polyposis coli (APC) function initiates tumorigenesis and that additional genetic and epigenetic events are involved in colon(More)