Wenhua Jia

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We have exploited a prandial insulin analog to elucidate the underlying structure and dynamics of insulin as a monomer in solution. A model was provided by insulin lispro (the active component of Humalog(®); Eli Lilly and Co.). Whereas NMR-based modeling recapitulated structural relationships of insulin crystals (T-state protomers), dynamic anomalies were(More)
Content-based image retrieval (CBIR) methods usually adopt color, texture and structure as image feature vector. Recent research indicates that since these features are not exactly associated with image semantic meaning, Query-By-One-Example (QBOE), which means to query with only one image, usually is insufficient to achieve good performance. Thus,(More)
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